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Is Frisage Collagen Drink safe? The Food & Drug Administration (FDA) classifies ingestible collagen as Generally Regarded As Safe (GRAS). Frisage Collagen Drink is manufactured in the USA by a leading manufacturer of food products and components following stringent GMP (good manufacturing practices). Each ingredient in the Frisage Collagen Drink formula and each production batch of Frisage is tested and certified safe. Frisage Collagen Drink is packaged in sealed bottles for optimal sterility and integrity.